{"id":126,"date":"2026-01-29T07:02:11","date_gmt":"2026-01-29T07:02:11","guid":{"rendered":"http:\/\/localhost:8000\/?post_type=news&p=117"},"modified":"2026-07-01T22:54:18","modified_gmt":"2026-07-01T22:54:18","slug":"development-validation-and-implementation-of-a-pharmaceutical-facility-disinfection-program","status":"publish","type":"news","link":"https:\/\/sterile.com\/fr\/news\/development-validation-and-implementation-of-a-pharmaceutical-facility-disinfection-program\/","title":{"rendered":"\u00c9laboration, validation et mise en \u0153uvre d'un programme de d\u00e9sinfection des installations pharmaceutiques"},"content":{"rendered":"

Pour lire cet article, rendez-vous sur le journal PDA Journal of Pharmaceutical Science Technology en cliquant ici. ce lien<\/a>.<\/h1>\n

R\u00e9sum\u00e9<\/h3>\n

Maintenir une ma\u00eetrise microbienne dans les milieux de fabrication pharmaceutique est une pierre angulaire des bonnes pratiques de fabrication (GMP). Cette revue compl\u00e8te pr\u00e9sente l\u2019\u00e9laboration, la validation et la mise en \u0153uvre de programmes de nettoyage et de d\u00e9sinfection robustes pour les installations pharmaceutiques, notamment les salles blanches, les syst\u00e8mes de barri\u00e8re d\u2019acc\u00e8s restreint (RABS) et les isoloirs. L\u2019article int\u00e8gre les attentes r\u00e9glementaires de l\u2019FDA des \u00c9tats-Unis (21 CFR 211), l\u2019annexe 1 de la GMP de l\u2019UE, ainsi que des documents de directives de l\u2019industrie tels que USP , PDA TR70 et IEST RP 18.5, en mettant l\u2019accent sur l\u2019importance des \u00e9tudes d\u2019efficacit\u00e9 des d\u00e9sinfectants bas\u00e9s en laboratoire ainsi que des essais in situ sur le terrain. Parmi les principaux sujets abord\u00e9s figurent la s\u00e9lection et le renouvellement des d\u00e9sinfectants et des agents sporicides, les m\u00e9thodologies de validation, les strat\u00e9gies de surveillance de l\u2019environnement et le r\u00f4le du peroxyde d\u2019hydrog\u00e8ne vaporis\u00e9 (VHP) dans la bio-d\u00e9sinfection. Des \u00e9tudes de cas et des analyses fond\u00e9es sur des donn\u00e9es illustrent les bonnes pratiques pour assurer la ma\u00eetrise de la contamination, notamment la validation de la propret\u00e9 des \u00e9quipements et les protocoles de requalification. L\u2019article pr\u00e9conise une approche solide pour valider \u00e0 la fois les technologies de d\u00e9sinfection manuelles et automatis\u00e9es, offrant une perspective prospective sur la ma\u00eetrise de la contamination dans la fabrication pharmaceutique moderne.<\/p>","protected":false},"featured_media":28427,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"class_list":["post-126","news","type-news","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nDevelopment, Validation, and Implementation of a Pharmaceutical Facility Disinfection Program - Veltek<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sterile.com\/fr\/news\/development-validation-and-implementation-of-a-pharmaceutical-facility-disinfection-program\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Development, Validation, and Implementation of a Pharmaceutical Facility Disinfection Program - Veltek\" \/>\n<meta property=\"og:description\" content=\"To read this article, head to PDA Journal of Pharmaceutical Science Technology by clicking this link. 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