{"id":605,"date":"2026-02-26T18:22:47","date_gmt":"2026-02-26T18:22:47","guid":{"rendered":"https:\/\/sterilecomstg.wpenginepowered.com\/?post_type=news&p=605"},"modified":"2026-07-01T22:53:41","modified_gmt":"2026-07-01T22:53:41","slug":"in-situ-verification-of-disinfection-rotation-for-contamination-control","status":"publish","type":"news","link":"https:\/\/sterile.com\/fr\/news\/in-situ-verification-of-disinfection-rotation-for-contamination-control\/","title":{"rendered":"V\u00e9rification in situ de la rotation des d\u00e9sinfectants pour le contr\u00f4le de la contamination"},"content":{"rendered":"

Pour lire cet article, rendez-vous sur le journal PDA Journal of Pharmaceutical Science Technology en cliquant ici. ce lien<\/a>.<\/h1>\n

R\u00e9sum\u00e9<\/h2>\n

Objectif : Les soci\u00e9t\u00e9s pharmaceutiques utilisent depuis de nombreuses ann\u00e9es diff\u00e9rents d\u00e9sinfectants pour les salles blanches. Toutefois, les raisons de cette rotation n\u2019ont pas toujours \u00e9t\u00e9 claires et, si cette question est pos\u00e9e \u00e0 plusieurs scientifiques, on s\u2019attend \u00e0 ce que des raisons vari\u00e9es soient invoqu\u00e9es. Il est \u00e0 pr\u00e9voir que les autorit\u00e9s r\u00e9glementaires exigeront \u00e9galement la rotation des d\u00e9sinfectants, mais la r\u00e9glementation \u00e9crite qui en donne les indications est consid\u00e9r\u00e9e comme assez vague. L\u2019annexe 1 de la nouvelle r\u00e9glementation GMP de l\u2019Union europ\u00e9enne (UE) \u2018 Fabrication de produits m\u00e9dicinaux st\u00e9riles \u2019 fait express\u00e9ment r\u00e9f\u00e9rence \u00e0 la rotation d\u2019un d\u00e9sinfectant sporicide dans le cadre du r\u00e9gime. Toutefois, il n\u2019existe toujours pas de directives quant au nombre ou aux types de d\u00e9sinfectants \u00e0 utiliser, ni quant \u00e0 la fr\u00e9quence de la rotation.<\/p>\n

M\u00e9thodes et r\u00e9sultats : Cette \u00e9valuation des r\u00e9sultats des essais de surveillance environnementale in situ \u00e0 quatre sites de fabrication r\u00e9pond \u00e0 la question de savoir si le remplacement de plus d\u2019un d\u00e9sinfectant \u00e0 large spectre par un autre est plus efficace que l\u2019utilisation d\u2019un seul d\u00e9sinfectant dans un r\u00e9gime de d\u00e9sinfection.<\/p>\n

Conclusion : Dans cette \u00e9tude, qui a inclus quatre sites de fabrication, il a \u00e9t\u00e9 d\u00e9montr\u00e9 que l\u2019utilisation d\u2019un d\u00e9sinfectant \u00e0 large spectre unique et d\u2019un sporicide \u00e9tait plus efficace que la rotation de deux d\u00e9sinfectants \u00e0 large spectre et d\u2019un sporicide.<\/p>\n

Importance et impact : Cette \u00e9valuation fournit des donn\u00e9es d\u00e9montrant que le fait de remplacer deux d\u00e9sinfectants \u00e0 spectre large et un sporicide par un seul d\u00e9sinfectant \u00e0 spectre large et un sporicide n\u2019apporte pas n\u00e9cessairement de b\u00e9n\u00e9fices en mati\u00e8re de contr\u00f4le de l\u2019environnement. Cette situation a des implications plus larges en ce qui concerne la remise en question du paradigme selon lequel le remplacement de plus d\u2019un d\u00e9sinfectant \u00e0 spectre large dans un environnement de salle blanche est pr\u00e9f\u00e9rable ou b\u00e9n\u00e9fique.<\/p>","protected":false},"featured_media":28427,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"class_list":["post-605","news","type-news","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nIn-situ Verification of Disinfection Rotation for Contamination Control - Veltek<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sterile.com\/fr\/news\/in-situ-verification-of-disinfection-rotation-for-contamination-control\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"In-situ Verification of Disinfection Rotation for Contamination Control - Veltek\" \/>\n<meta property=\"og:description\" content=\"To read this article, head to PDA Journal of Pharmaceutical Science Technology by clicking this link. 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